French modify polio plant in India

Polio eradication in India: pulse polio immunization.

The magnitude of the public health program for the eradication of poliomyelitis launched by the Government of India and the State Governments has few parallels. Over 87.77 million children, including 79.29 million children less than three years of age, were given a dose of oral polio on one day throughout the country on 9 December 1995. In the second round on 20 January 1996 over 93.118 million...

Update on Chikungunya and polio in India.

INDIAN PEDIATRICS 39 VOLUME 45__JANUARY 17, 2008 In the last two years, Chikungunya has become a household name in India. This mosquito borne illness has derived its name form Makonde language word for ‘to bend up’as the severe arthralgia compels the affected patient to acquire a stooped posture for obtaining relief. The Chikungunya fever is caused by Chikungunya virus (CHKV) belonging to Togav...

Vaccine-associated paralytic polio in India.

Polio eradication. Efficacy of inactivated poliovirus vaccine in India.

Inactivated poliovirus vaccine (IPV) is efficacious against paralytic disease, but its effect on mucosal immunity is debated. We assessed the efficacy of IPV in boosting mucosal immunity. Participants received IPV, bivalent 1 and 3 oral poliovirus vaccine (bOPV), or no vaccine. A bOPV challenge was administered 4 weeks later, and excretion was assessed 3, 7, and 14 days later. Nine hundred and ...

Severe vitamin A deficiency in India during pulse polio immunization.

Although this assessment of children monitored during the pulse polio rounds does not serve as a formal vitamin A deficiency survey, the number of children assessed and the large number of sites sampled exceeded the minimum numbers of children and clusters required for the most basic vitamin A deficiency survey using night blindness as the main indicator (3,042 children and 30 cluster). The WHO...